Yes, the USB Isolator Module (ADUM4160/3160) is fully compatible with Arduino, Raspberry Pi, ESP boards, and most USB-based development tools.
It provides electrical isolation between the host computer and USB devices, protecting both sides from noise, ground-loops, voltage spikes, and potential damage during testing or debugging. This makes it ideal for safely interfacing programmers, debuggers, USB-serial adapters (FT232, CP2102, CH340), JTAG tools, and diagnostic modules with microcontroller boards.
The isolator ensures stable, clean USB communication—especially useful in robotics, power electronics, high-noise environments, and sensitive embedded development setups.